Extended Data Fig. 9: Trans-infection neutralization.
From: Lectins enhance SARS-CoV-2 infection and influence neutralizing antibodies
HeLa cells transduced with DC-SIGN (a) or SIGLEC1 (b) were incubated with VSV-SARS-CoV-2, extensively washed and incubated with serial dilutions of anti-spike antibodies. After 30 min, susceptible target cells (Vero-E6-TMPRSS2) were added for co-culture. Luminescence signal was quantified 24h post co-culturing to determine trans-infection levels (n = 3 biologically independent replicates).
