Extended Data Fig. 1: Histological validation of implanted sites.
From: Dopamine facilitates associative memory encoding in the entorhinal cortex
(a). Optic fibre positions in the LEC of Sim1-Cre mice injected with AAV-flex-Jaws-GFP for inhibition experiments. Arrowhead, the tip of optic fibres. D, dorsal, V, ventral, M, medial, L, lateral. (b). Optic fibre positions in the LEC of Wfs1-Cre mice for inhibition experiment of Wfs1-expresing pyramidal cells. (c). Recording position in the superficial layer of LEC from Sim1-Cre mice for opt-tagging experiment. Note large lesions because of the electrical lesioning. (d). Optic fibre positions in the LEC of DAT-Cre mice injected with AAV-flex-Jaws-GFP in the VTA/SNc for inhibition experiment. (e). Optic fibre positions in the LEC of DAT-Cre x Ai14 mice for photometry experiment. Two mice received unilateral implantations and four mice received bilateral implantations. (f). Recording position in the superficial layer of LEC from Sim1-Cre x DAT-Cre mice for opt-tagging + inhibition experiment. (g). Optic fibre positions in the LEC of Sim1-Cre mice injected with AAV-flex-GFP for control inhibition experiment. (h). Optic fibre positions in the LEC of Wfs1-Cre mice injected with AAV-flex-GFP for control inhibition experiment. (i). Optic fibre positions in the LEC of DAT-Cre mice injected with AAV-flex-GFP at VTA and SNc for control inhibition experiment. (j). Recording position in the superficial layer of LEC from Sim1-Cre x DAT-Cre mice for opt-tagging (ChR2-mCherry) + control inhibition (GFP) experiment.
