Extended Data Fig. 5: Conservation of CBLN2 E2 and deleted regions across species.
From: Hominini-specific regulation of CBLN2 increases prefrontal spinogenesis
Phylogenetic tree of selected chordates including placental and non-placental mammals with information about presence of the CBLN2/Cbln2 gene and CBLN2 E2/Cbln2 E2. The last three columns describe the presence of HSD1, HSD2 and I3. The mouse E2 sequence was searched in each most updated animal genome browser at UCSC genome browser (as of December 22, 2019). E2 conservation criteria are: 1) identity over 80%; and 2) alignment length over 600 bp compared with mouse E2 (1005 bp).
