Extended Data Fig. 2: Cell type identification and isoform summary statistics.
From: Isoform cell-type specificity in the mouse primary motor cortex
a) Comparison of subclass identification for 10xv3 and SMART-seq. Each technology identified subclasses separately, but with the same method. 56 clusters with gene markers were identified in the 10xv3 data but not in the SMART-seq data while 39 clusters with gene markers were identified in the SMART-seq data and not the Chromium data. b) The distribution of the number of isoforms per gene within each of 18 subclasses, computed from the top 998 most highly expressed genes in the SMART-seq dataset. The number associated with each class indicates the fraction of genes for which there are more than one isoform. c) Extent of isoform diversity in groups of transcripts sharing a 3′ end. Each point displays the density of the number of groups (y-axis) containing a given number of isoforms (x-axis) for a single gene. Points along the line y = x correspond to genes where all transcripts contained within the gene have unique 3′ ends.
