Extended Data Fig. 7: Nuclear–cytoplasmic ratios for wild-type and mutant FOXO1-GFP constructs in HCC cell lines.
From: Convergent somatic mutations in metabolism genes in chronic liver disease
a, b, Wide-field view of Hep3B (a) and PLC/PRF5 (b) cells pseudocoloured on a blue-to-red scale by the nuclear-cytoplasmic ratio of FOXO1-GFP. Cells were imaged under conditions of serum starvation (left), after exposure to insulin 100nM for 15 min (middle) or foetal calf serum (FCS) for 15 min (right).
