Fig. 3: IR flexibility increases central channel size in native NPCs.
From: The cellular environment shapes the nuclear pore complex architecture
a, Segmentation of the IR from our model and the previous human NPC model. The IR diameter (membrane to membrane) and central channel diameter measurements are indicated. The IR channel volume was calculated as a cylinder with a height of 20 nm. b, Top view of three IR subunits in our model compared with the previous model. c, Schematic showing the lock-and-key-like architecture of the previous model and how the IR subunits have shifted in our model.
