Extended Data Fig. 4: Details of the Y complex assembly in CR and NR.
From: The cellular environment shapes the nuclear pore complex architecture
a, Cartoon model for the human composite Y complex that was docked into the CR of our cryo-ET density map. b, Zoom-in view of the docked Y complex model in the CR with additional density connecting the two Y rings attributed to the Nup358 complex (green arrowhead). c, Zoom-in view of the docked Y complex model in the NR with additional density connecting the two Y rings (red arrowhead). d, Comparison of CR sub-structures from our study and the previous human model. Arrowheads indicate density attributed to the Nup358 complex (green), Nup214 complex (blue), and an unassigned density we observe at the Nup85 arms (black). e, Same as (d), but for NR. Black arrowheads indicate similar density at Nup85 arms as in CR. f, Comparison of cross-section views of the NPC with dashed red line to indicate the orientation of the Y complexes with respect to the nuclear membranes.
