Extended Data Fig. 3: HSV-1 ΔICP0 is attenuated in BLaER1 monocytes.
From: Self-guarding of MORC3 enables virulence factor-triggered immunity
(a) BLaER1 monocytes were infected with HSV-1 at indicated MOI and protein expression was analyzed by immunoblot at indicated timepoints. Data is depicted as one representative of two experiments. (b) BLaER1 monocytes were infected with HSV-1 at MOI = 1 and viral progeny was quantified in the supernatant. Mean of five independent experiments is shown. (c) BLaER1 monocytes were infected with HSV-1 at indicated MOI and analyzed by flow cytometry. Mean + SEM of three independent experiments is depicted. Data is duplicated in Fig. 3b. * p < 0.05; *** p < 0.001; ns = not significantly different than HSV-1 WT, tested by two-way ANOVA and Bonferroni’s post hoc test. See Source Data for exact p values
