Extended Data Fig. 10: Full psychometric functions of individual mice in the sparseness task.
From: Thalamic circuits for independent control of prefrontal signal and noise
Performance accuracy in the distributed cue task with input uncertainty due to cueing sparseness, separated by animals. For each animal, performance accuracy consistently diminishes with decreasing signal (black traces), while optical inhibition of PL→MD terminals (yellow traces) during the cueing period generally reduces performance more strongly on low signal trials than on high signal trials (M1: p = 0.644 (NS; relative signal = 0.25), *p = 0.0348 (relative signal = 0.13); M2: p = 0.676 (NS; relative signal = 0.25), *p = 0.0426 (relative signal = 0.13); M3: p = 0.139 (NS, relative signal = 0.25), p = 0.0604 (NS; relative signal = 0.13); M4: p = 0.343 (NS; relative signal = 0.25), **p = 0.0251 (relative signal = 0.13); chi-squared test). Inset in each panel highlights the inactivation effect on trials with high (0.25) and low (0.13) signal. All statistical tests are two-tailed. For inset box plots, boundaries, 25–75th percentiles; midline, median; whiskers, minimum–maximum. Data are presented as mean ± SEM
