Extended Data Fig. 2: Somatic impedance profiles and voltage sag. Related to Fig. 1.
From: Allometric rules for mammalian cortical layer 5 neuron biophysics
a-d, Somatic impedance profiles (Etruscan shrew n = 29, mouse n = 71, gerbil n = 39, rat n = 64, ferret n = 28, guinea pig n = 35, rabbit n = 37, marmoset n = 30, macaque n = 25, human n = 100). Pooled data represent mean ± SEM for a-b. Box plots denote the median and 25–75th percentiles for c-d. a, Impedance profile in response to sinewaves of 50-100 pA injected at the indicated frequencies for 2 s. b, Phase offset between the voltage response and the injected current. c, Maximal impedance (p < 10−49 Kruskal-Wallis; χ2 = 259 & 9 df). d, Resonance frequency (p < 10−13 Kruskal-Wallis; χ2 = 81 & 9 df). Data points displayed as a beeswarm plot to show overlapping integers. e, Somatic voltage sag (p < 10−57 Kruskal-Wallis, χ2 = 298 & 9 df; Etruscan shrew n = 39, mouse n = 85, gerbil n = 58, rat n = 117, ferret n = 31, guinea pig n = 47, rabbit n = 40, marmoset n = 41, macaque n = 34, human n = 126). Box plots denote the median and 25–75th percentiles.
