Extended Data Fig. 4: Efficiency of plating on cells expressing Thoeris systems of B. cereus, B. dafuensis and hybrid systems.
From: Antiviral activity of bacterial TIR domains via immune signalling molecules
a, EOP of phages on control cells (black) and cells expressing combinations of ThsA from either B. cereus (green) or B. dafuensis (blue), TIR protein from B. cereus (ThsB), TIR proteins from B. dafuensis (TIR1 and TIR2) or both TIRs from B. dafuensis (TIR1+TIR2). Bars represent mean of 3 replicates, with individual data points overlaid. Asterisk marks statistically significant reduction in EOP (One-way ANOVA, followed by pairwise multiple comparison analysis according to Tukey’s honest significant difference criterion p<0.0015). b, EOP of phages on control cells (black) and cells expressing mutant ThsA(N112A) from B. cereus together with combinations of TIR proteins from B. cereus and B. dafuensis.
