Fig. 2: Potency and breadth of neutralization of nAbs against SARS-CoV-2 and VoCs.
From: Hybrid immunity improves B cells and antibodies against SARS-CoV-2 variants
a–e, Scatter dot charts show the neutralization potency, reported as IC100 (ng ml−1), of nAbs tested against the original SARS-CoV-2 virus first detected in Wuhan (a) and the B.1.1.7 (b), B.1.351 (c), B.1.1.248 (d) and B.1.617.2 (e) VoCs. The number and percentage of nAbs from individuals who were seronegative versus seropositive, fold change, neutralization IC100 geometric mean (black lines, blue and red bars) and statistical significance are denoted on each graph. A non-parametric Mann–Whitney t-test was used to evaluate statistical significances between groups. Two-tailed P value significances are shown as *P < 0.05, **P < 0.01, ***P < 0.001. NS, not significant. f, The table shows the IC100 geometric mean (GM) of all nAbs pulled together from each group against all SARS-CoV-2 viruses tested. Technical duplicates were performed for each experiment.
