Extended Data Fig. 4: Heavy chain CDR3 length and somatic hypermutation levels in seronegative and seropositive vaccinees.
From: Hybrid immunity improves B cells and antibodies against SARS-CoV-2 variants

a, The graph shows the heavy chain CDR3 length represented in amino acids (aa). b, The graph shows the overall somatic hypermutation level of nAbs isolated from seronegative and seropositive vaccinees. Geometric mean and standard deviation are denoted on the graphs. A nonparametric Mann–Whitney t test was used to evaluate statistical significances between groups. Two-tailed p-value significances are shown as *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001.