Extended Data Fig. 7: Selective targeting of T cells and ILC3s through RORγt.
From: Antigen-presenting innate lymphoid cells orchestrate neuroinflammation
a, Expression of MHCII was quantified by flow cytometry in indicated antigen-presenting cells from the cLN or CNS of indicated mice at steady state (n = 4 mice/group). b-c Representative flow cytometry gating strategy for indicated immune cell populations in the CNS (b) and expression of YFP in indicated cell populations and tissues (c) of Rorc-creeYFP mice at day 15 of active EAE. d, Reverse flow cytometry gating strategy defining all YFP+ fate-mapped cells in the CNS of Rorc-creeYFP mice (day 15 EAE) (Lin 1 = B220, CD11b, CD11c, Lin 2 = CD3ε, CD5, CD8, Ly6C). Results are shown as mean ± s.d. Statistics are calculated by one-way analysis of variance (ANOVA) with Sidak’s multiple comparisons test (a). Data in a-d are representative of two independent experiments with similar results
