Extended Data Fig. 9: Whole cell patch-clamp electrophysiology of the mutations of different glycine residues along the TM6 helix.
From: The conformational cycle of prestin underlies outer-hair cell electromotility
All the individual data points, that has been averaged in Fig. 3f, has been presented here. Compared to wild-type prestin, mutation of evolutionary conserved glycine residues, a, G274 and G275 and b, G263, G265 and G270 largely affects the NLC.
