Extended Data Fig. 7: Vaccine-induced IFNγ T cell response to CoVac-1 peptides affected by mutations of SARS-CoV-2 variants of concern (VOC). | Nature

Extended Data Fig. 7: Vaccine-induced IFNγ T cell response to CoVac-1 peptides affected by mutations of SARS-CoV-2 variants of concern (VOC).

From: A COVID-19 peptide vaccine for the induction of SARS-CoV-2 T cell immunity

Extended Data Fig. 7

CoVac-1-induced T cell response to the single wild-type (WT) CoVac-1 peptides (P2_nuc (nucleocapsid), P3_spi (spike), P6_ORF8 (open reading frame 8)) in comparison to corresponding peptides comprising mutations of B.1.1.7-Alpha and B.1.351-Beta VOC were assessed by ex vivo IFNγ ELISPOT assay for (a) P2_nuc, (b) P3_spi, and (c) P6_ORF8 using PBMCs from study participants (n = 4) collected on day 28 after CoVac-1 vaccination.

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