Extended Data Table 2 MIC values for macolacin analogs with different lipid substituents.

From: A naturally inspired antibiotic to target multidrug-resistant pathogens

  1. Note: For pathogens that are not intrinsically resistant to colistin, the fold increase in MIC upon introduction of mcr-1 is shown in bold. L1-L14 are the macolacin analogs shown in Extended Data Fig. 3. L6 is biphenyl-macolacin. S = colistin sensitive, R = colistin resistant, Col = colistin, Mac = macolacin. Each MIC was measured in technical duplicate and on at least two independent occasions with the same results.
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