Extended Data Table 3 Pharmacokinetic parameters following a single subcutaneous administration of GS-CA1 in rhesus macaques

From: Long-acting capsid inhibitor protects macaques from repeat SHIV challenges

  1. Pharmacokinetic parameters, including area under the plasma concentration–time curve from time 0 to the last quantifiable time point (AUClast), area under the plasma concentration–time curve from time 0 to infinity (AUCinf), maximal concentration (Cmax), time to reach observed peak plasma concentration (Tmax), and terminal half-life (t1/2) determined by non-compartmental analysis using Phoenix WinNonlin 6.4 build 8.1.0.3530. CV, coefficient of variation (100 X standard deviation / mean).
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