Extended Data Fig. 8: Gating strategy and pseudolongitudinal time course of transcription factor expression. | Nature

Extended Data Fig. 8: Gating strategy and pseudolongitudinal time course of transcription factor expression.

From: Signature of long-lived memory CD8+ T cells in acute SARS-CoV-2 infection

Extended Data Fig. 8

a, Gating strategy TCF1+, T-BET+, EOMES+, and TOX+ cells in CoV2-Dex and CoV2-Dex+ cells. b, Percentages of TCF1+, T-BET+, EOMES+, and TOX+ cells in CoV2-Dex and CoV2-Dex+ cells (left) six months and (right) one year after infection (n = 24 six months, n = 29 one year). c, Linear regression of frequencies of TCF1+, T-BET+, EOMES+, and TOX+ cells in CoV2-Dex+ cells as a function of time since symptom onset (n = 81). P-values were calculated with t-statistic. d, Expression of transcription factors in Teffector/TEM and TEMRA in CoV2-Dex+ cells in acute infection and six months and one year after infection (n = 24 acute, n = 24 six months, n = 26 one year). P-values were calculated using a Wilcoxon signed-rank test in b and d. All tests were performed two-sided.

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