Extended Data Fig. 1: Gating strategy for antigen-specific CD8⁺ T cells and SARS-CoV2-specific antibodies in healthy donors and COVID-19 patients.

a, Gating strategy for CoV2-Dex⁺ cells. b, Representative plot of CoV2-Dex staining for HLA-A*11:01 and HLA-A*24:02. c, Gating strategy for CoV2-Pent⁺ cells. d, Linear regression of frequency of CoV2-Dex⁺ cells as a function of frequency of CoV2-Pent⁺ cells (n = 7). The p-value was calculated with t-statistic. e, SARS-CoV2-specific IgA (left) and IgG (right) of healthy donors compared to COVID-19 patients during acute infection, six months and one year after infection (n = 13 healthy , n = 46 acute, n = 41 six months, n = 30 one year). Dashed lines represent diagnostic cut-off values, i.e., 2.0 and 1.1 for IgA and IgG, respectively. P-values were calculated with a Mann-Whitney-Wilcoxon test. All tests were performed two-sided.