Fig. 3: Expanding Coronaviridae. | Nature

Fig. 3: Expanding Coronaviridae.

From: Petabase-scale sequence alignment catalyses viral discovery

Fig. 3

a, Phylogram for group-E sequences. Six viruses were similar to PsNV in Ambystoma mexicanum (axolotl; AmexNV), Puntigrus tetrazona (tiger barb; PtetNV), Hippocampus kuda (seahorse; HkudNV), Syngnathus typhle (broad-nosed pipefish; StypNV), Takifugu pardalis (fugu fish; TparNV) and the Acanthemblemaria sp. (blenny; AcaNV). More-distant members identified were in Hypomesus transpacificus (the endangered delta smelt; HtraNV), Silurus sp. (catfish; SilNV) and Monopterus albus (asian swamp eel; MalbNV). b, Unrooted phylogram for Coronaviridae annotated with genera (Greek letters) and group-E CoV-like nidoviruses (see also Extended Data Fig. 4). Maximum likelihood tree generated by clustering the RdRP amino acid sequences at 97% identity to show sub-species variability. c, Genome structure of AmexNV and the contigs recovered from group-E CoV-like viruses annotated with HMM matches. AmexNV contigs contain an identical 129-nt trailing sequence (Tr). All the putatively segmented CoV-like are monophyletic with PsNV. A gap in the PsNV reference sequence24 is shown with circles, overlapping the common contig ends seen in these viruses.

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