Extended Data Fig. 1: Trpγ is necessary for PSINA. | Nature

Extended Data Fig. 1: Trpγ is necessary for PSINA.

From: A discrete neuronal population coordinates brain-wide developmental activity

Extended Data Fig. 1

a. Raw values binned by hour for active phase signal amplitude, sweeps/cycle, cycles/hour, and cycle duration for control (black, n=19) and trpγ null (orange, n=31) pupae. Shaded areas, SD. b. Active phase average amplitude (left) and sweeps/cycle (right) binned by hour and normalized to control activity during the turbulent stage, between 65 and 80 hAPF, for control (black, n=19), trpγ null (orange, n=31), and trpγ null with Trpγ-D expressed in Trpγ+ cells (cyan, n=4) pupae. Shaded areas, SD. c. Cycle duration (left) and cycles/hour (right) binned by hour and normalized to control activity between 55 and 65 hAPF. Shaded areas, SD. Genotypes color-matched to B. d. Representative traces of activity in control (black, n=19), trpγ/TrpγG4 (orange, n=5), trpγ/TrpγDropIn-TG4 (gray, n=5), trpγ/Df(2L)1102 (magenta, n=7), and trpγ/Df(2L)1109 pupae (green, n=7). e. Average amplitude (left) and sweeps/cycle (right) binned by hour and normalized to control activity between 55 and 65 hAPF. Shaded areas, SD. Genotypes color-matched to D. f. Active phase average amplitude (left) and sweeps/cycle (right) binned by hour and normalized to control activity during the periodic stage, between 55 and 65 hAPF, for control (black, n=10), trpγ null (orange, n=9), trp null (blue, n=10), and trp null + trpγ null (green, n=10). Shaded areas, SD. g. Active phase average amplitude (left) and sweeps/cycle (right) binned by hour and normalized to control activity during the periodic stage, between 55 and 65 hAPF, for control (black, n=10), trpγ null (orange, n=10), trpL null (blue, n=10), and trpL null+ trpγ null (green, n=10). Shaded areas, SD.

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