Extended Data Fig. 1: Virus replication of Omicron, WT SARS-CoV-2, and other VOCs in Caco2 and VeroE6 cells.
From: Attenuated replication and pathogenicity of SARS-CoV-2 B.1.1.529 Omicron

a Caco2 and b VeroE6 cells were challenged by SARS-CoV-2 WT, Alpha, Beta, Delta, Omicron, or Omicron(R346K) at 0.1 m.o.i. Cell lysates were harvested at the designated time points for the quantification of subgenomic RNA of the envelope (sgE) gene. Robustness of sgE production was quantified with the AUC analysis (n = 7). Data represents mean ± SD from the indicated number of biological repeats. Statistical significances were determined with one-way ANOVA with Tukey’s multiple comparison tests. Each data point represents one biological repeat. * represented p < 0.05 and ** represented p < 0.01. *** represented p < 0.001, **** represented p < 0.0001. ns, not statistically significant.