Extended Data Fig. 6: Impact of prior COVID-19 infection on T cell responses to the ancestral and Omicron SARS-CoV-2 spike in vaccinated participants.
From: T cell responses to SARS-CoV-2 spike cross-recognize Omicron
a, Comparison of the frequency of ancestral spike-specific T cell responses in vaccinated participants who had (Y) or did not have (N) prior SARS-CoV-2 infection. Pies depict the proportion of participants exhibiting a detectable CD8+ T cell response. Bars represent medians. Statistical differences were calculated using a two-tailed Mann-Whitney test. b, Fold change in the frequency of spike-specific CD4+ T cells between ancestral and Omicron spike responses in the three vaccine groups. Bars represent medians. Statistical differences were calculated using a two-tailed Mann-Whitney test. The number of participants included in each analysis is indicated on the graphs.
