Extended Data Fig. 8: Pathway analysis.
From: Molecular hallmarks of heterochronic parabiosis at single-cell resolution
a, Top 10 most differently affected pathways over all ACC tissues and cell types (top, largest difference at the top) and top 10 most differently affected pathways over all AGE (bottom, largest difference at the bottom) tissues and cell types. b, Same as for a, comparing REJ and AGE pathways. c, Heatmap showing the top 30 most strongly affected pathways in AGE, ACC and REJ in hematopoietic stem cells (HSCs) of the marrow. Pathways related to mitochondria are highlighted in green on the left. Each entry of the heatmap shows the significance level and the number of genes associated with the pathway. d, Same as for c, showing the top 30 most strongly affected pathways for beta cells of the pancreas.
