Fig. 2: Structural differences between Ste2–Ant and Ste2–Ag–G.
From: Activation mechanism of the class D fungal GPCR dimer Ste2
a, b, Superposition of Ste2–Ant (rainbow coloration) and Ste2–Ag–G (grey) with ligands shown as sticks (antagonist, purple carbon atoms; α-factor, grey carbon atoms). Major changes in secondary structure positions are indicated by arrows. a, Extracellular view. b, Intracellular view. c, Individual helices are shown after global alignment of Ste2 in different conformational states (colouration as in a).
