Extended Data Fig. 8: Human ASPCs exhibit strong depot dependency while mouse ASPCs are dependent on both depot and diet.
From: A single-cell atlas of human and mouse white adipose tissue
a, b, UMAP projections of human (a) and mouse (b) ASPCs split by depot. c-d, UMAP projections of human (c) and mouse (d) ASPCs split by BMI/diet. e, f, Proportion of ASPC cells in each cluster per sample split by depot and BMI for human (e) and depot, diet, and sex for mouse (f). For humans, n = 11 SAT < 30, 6 SAT > 40, 3 VAT < 30, and 5 VAT > 40. For male mice n = 4 ING Chow, 4 ING HFD, 3 EPI Chow, and 5 EPI HFD. For female mice, n = 2 per condition. For bar graphs, error bars represent SEM, * indicates credible depot effect and # indicates credible BMI/diet effect, calculated using hASPC2 (human) and mASPC4 (mouse) as reference.
