Extended Data Fig. 5: Human and mouse immune cells are differentially regulated by depot and BMI/diet.
From: A single-cell atlas of human and mouse white adipose tissue
a, b, UMAP projections of human (a) and mouse (b) WAT immune cells split by depot. c, d, UMAP projections of human (c) and mouse (d) WAT immune cells split by BMI (c) and diet (d). e-f, Bar graphs showing the proportion of cells in each cluster per sample split by depot and BMI for human (e) and depot, diet, and sex for mouse (f). For humans, n = 10 SAT < 30, 6 SAT > 40, 3 VAT < 30, and 5 VAT > 40. For male mice n = 4 ING Chow, 4 ING HFD, 3 EPI Chow, and 5 EPI HFD. For female mice, n = 2 per condition. For bar graphs, error bars represent SEM, * indicates credible depot effect and # indicates credible BMI/diet effect, calculated using hMono2 (human) and mcDC1 (mouse) as reference.
