Extended Data Fig. 5: Zonation in human brain endothelial cells. | Nature

Extended Data Fig. 5: Zonation in human brain endothelial cells.

From: Single-cell dissection of the human brain vasculature

Extended Data Fig. 5

a. Gene zonation analysis of mouse brain endothelial cells from Vanlandewjick et al. b. Integrated zonation analysis of human and mouse brain endothelial cell profiles. Pearson correlation coefficient of shared genes shown on right. c. Indirect immunofluorescence of TSHZ2 expression in human and mouse brain cortex. d. Indirect immunofluorescence of MT1E/MT1 expression in human and mouse brain cortex. e. Indirect immunofluorescence of MT2A/MT2 expression in human and mouse brain cortex. f. Enriched Gene Ontology terms in endothelial zones. Representative images in c., d., and e. from n = 3 independent biological replicates for each marker. Brightness and contrast enhanced for visualization. Scale bar, 20 μm.

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