Extended Data Fig. 6: Display of MANE data in Ensembl.
From: A joint NCBI and EMBL-EBI transcript set for clinical genomics and research
(A) In Ensembl’s Gene page, the Ensembl/GENCODE transcript(s) in the MANE set is highlighted with the “MANE Select” or “MANE Plus Clinical” flags, visible in the last column of the transcript table. The identical RefSeq transcript is highlighted in the same table, in the column titled “RefSeq Match”. (B) Graphical representation is visible in the Location page after configuring the view by adding the custom-made MANE Project track hub (https://ftp.ncbi.nlm.nih.gov/refseq/MANE/trackhub/hub.txt). (C) The list of MANE transcripts can be accessed and downloaded from Ensembl’s Transcript Archive (Tark) MANE Project page (http://tark.ensembl.org/web/manelist) and programmatically using APIs available in the REST API page (http://tark.ensembl.org/api/#!/transcript/transcript_manelist_list), or Ensembl’s REST API e.g. https://rest.ensembl.org/overlap/id/ENSG00000128573?feature=mane;content-type=text/xml. (D) MANE data can also be downloaded from Ensembl BioMart (https://www.ensembl.org/biomart/martview/c24cb3213fe65da552fcb8b755c2910c) by choosing the ‘Human Genes (GRCh38.p13) dataset and the ‘MANE transcripts’ filter.
