Extended Data Fig. 7: Competition experiments indicated the miniprotein binders bound to the targeted region.
From: Design of protein-binding proteins from the target structure alone
Yeast cells displaying the TrkA binder (a), InsulinR binder (b), IGF1R binder (c), PDGFR binder (d) and Tie2 binder (e) were incubated with the target protein in the presence or absence of the native ligand as the competitor, and target protein binding to cells (y axis) was monitored with flow cytometry.
