Extended Data Fig. 2: Alignment of human and mouse GSDMAs.
From: Group A Streptococcus induces GSDMA-dependent pyroptosis in keratinocytes
Human GSDMA (Q96QA5), mouse GSDMA_1 (Q9EST1), mouse GSDMA_2 (Q32M21), mouse GSDMA_3 (Q5Y4Y6) aligned with Clustal Omega algorithm in DNASTAR. Disordered solvent accessible loop (gray box). Inverted arrows identify cleavage sites of SpeB on hGSDMA. Residues 240–247 of hGSDMA are identified (green bar).
