Extended Data Fig. 7: Bulk RNAseq of hippocampal OPC and OL nuclei from young and aged mice. | Nature

Extended Data Fig. 7: Bulk RNAseq of hippocampal OPC and OL nuclei from young and aged mice.

From: Young CSF restores oligodendrogenesis and memory in aged mice via Fgf17

Extended Data Fig. 7

a, Gating strategy for sorting of hippocampal OPC and OL nuclei. b, Heatmap of expression OPC and OL specific genes across young and aged OPC and OL samples (aged OL n = 3, rest n = 4). c, Volcano plot showing OL genes up and downregulated with age (n = 4; p. adjusted value by Wald test in DESeq2). d, Pathways enriched (red) or depleted (blue) in hippocampal OLs with age (unweighted Kolmogorov-Smirnow test).

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