Extended Data Fig. 5: Gene expression patterns in Slc7a11 KO efferocytic dendritic cells.
From: Targeting SLC7A11 improves efferocytosis by dendritic cells and wound healing in diabetes
a, Heat maps comparing efferocytic Slc7a11 KO versus WT dendritic cells showing upregulation and downregulation of differentially expressed genes (0.58 ≤ Log2FC ≤ −0.58) that are associated with metabolic and mitochondrial function, protein synthesis, ER homeostasis, transcription regulation, signaling, wound healing, cell cycle, migration and other transporters. Data are from 3-4 independent experimental replicates. Gdf15 falls under the transcriptional programs of metabolic function and regeneration, and is highlighted in red.
