Extended Data Fig. 11: Replication of cardiac fibroblast activation assay across up to five screens.
From: Single-nucleus profiling of human dilated and hypertrophic cardiomyopathy
The percent change in the fraction of myofibroblasts across up to five screens for each sgRNA (independent sgRNAs denoted as “G”). Within each screen, well values were normalized to the median effect of TGFBR1 sgRNAs and non-targeting control sgRNAs. The specific screen replicate (Rep.) is shown above each respective bar where “P” indicates the primary screen, and r1-r4 indicate replicate screens 1–4. The number of wells included in each screen (Nwell) are displayed below each bar with individual dots displayed for each well value. Error bars depict standard error to the mean.
