Extended Data Fig. 1: Sample quality control assessment. | Nature

Extended Data Fig. 1: Sample quality control assessment.

From: Single-nucleus profiling of human dilated and hypertrophic cardiomyopathy

Extended Data Fig. 1

a, Distribution of key quality control metrics from CellRanger count as boxplots stratified by non-failing (NF, n = 32), dilated cardiomyopathy (DCM, n = 24), and hypertrophic cardiomyopathy (HCM, n = 32). Cutoffs for low quality are shown by the dashed line, and samples that fail on a given metric are labeled. Center line, median; box limits, upper and lower quartiles; whiskers, 1.5x interquartile range; points, outliers. b, Exemplar high quality UMI (unique molecular identifier) decay curves (green) and low quality UMI decay curves (red) are shown. Cell barcodes are ranked by the total UMI. c, Total counts from Y chromosome transcripts in phenotypically classified females (red) and males (blue) across all samples (n = 88).

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