Extended Data Fig. 9: Fractions of nonsynonymous (blue) and synonymous (yellow) neutral mutations in one environment (indicated on the X-axis) that become deleterious in any of the other three environments.
From: Synonymous mutations in representative yeast genes are mostly strongly non-neutral
The fractions are higher for nonsynonymous than synonymous mutations (P < 0.05, paired t-test). A mutation is considered deleterious if its fitness is significantly lower than 1 (P < 0.05) and neutral if its fitness is not significantly different from 1
