Extended Data Fig. 4: Data processing of WNT3Ap/LGK974-bound PORCN and pamWNT3Ap-bound PORCN.
From: Mechanisms and inhibition of Porcupine-mediated Wnt acylation
a, The data processing of WNT3Ap/LGK974-bound PORCN. The cryo-EM 3D classes as well as the mask used for the refinement are shown. The final cryo-EM map after cryoSPARC refinement was sharpened with a B-factor value of −147 Å2. b, Fourier shell correlation (FSC) curve of WNT3Ap/LGK974-bound PORCN map as a function of resolution using cryoSPARC output. c, The data processing of pamWNT3Ap-bound PORCN. The cryo-EM 3D classes as well as the mask used for the refinement are shown. The final cryo-EM map after cryoSPARC refinement was sharpened with a B-factor value of −140 Å2. d, Fourier shell correlation (FSC) curve of pamWNT3Ap-bound PORCN map as a function of resolution using cryoSPARC output.
