Extended Data Fig. 8: Single-nucleus transcriptome analysis in healthy and varying ischaemic conditions in the hippocampus, heart, liver, and kidney.
From: Cellular recovery after prolonged warm ischaemia of the whole body
a-d, From left to right: UMAP layout showing major t-types; UMAP layout, coloured by Augur cell type prioritization (AUC) between 0h WIT compared to 1h (up) and 7h WIT (down); statistical comparison of Augur AUC scores between 0h WIT and 1h (up) and 7h (down) of WIT; Volcano plot showing top DEGs in major annotated t-types between 0h and 1h WIT (up), or 0h and 7h WIT (down); GO terms associated with the genes up and downregulated in detected nuclei between 0h and 1h WIT (up), or 0h and 7h WIT (down) with their nominal P-value in respective major annotated t-types.
