Extended Data Fig. 10: Fos-KO and Fos-WT place field distribution. | Nature

Extended Data Fig. 10: Fos-KO and Fos-WT place field distribution.

From: Fos ensembles encode and shape stable spatial maps in the hippocampus

Extended Data Fig. 10

a) Normalized activity of Fos-KO (top) and Wt (bottom) place cells as a function of track position. b) Histogram of peak location for Fos-KO (green) and Wt (purple) cells. Vertical gray line denotes start of reward zone. c) Top: Distance of place fields from the reward zone for simultaneously recorded Fos-KO (Cre+) and wild-type (Wt) cellvs. Each circle indicates the mean across cells for one session. Bottom: Histogram of the differences between Cre+ and Wt values in the above scatter. p = 0.85; two-sided paired-sample t-test. n = 39 sessions, 6 mice. de) Average in-field and out-of-field activity for simultaneously recorded Fos-KO (Cre+) and wild-type (Wt) place cells, plotted as in (c). p = 0.03 (d), p = 0.0007 (e); two-sided paired-sample t-test.

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