Extended Data Fig. 2: Detailed time course of changes in Fos-GFP expression after behavior.
From: Fos ensembles encode and shape stable spatial maps in the hippocampus
a–b) GFP fluorescence from the Fos reporter mouse for representative fields-of-view (top) and zoomed in regions (middle) at four timepoints relative to the start of a behavior session. The fold-induction maps (bottom) are shown for the zoomed in areas. Arrows in (b) highlight three cells with appreciable increases in GFP fluorescence. c) Interpolated and smoothed time courses for the fold-change in GFP fluorescence from the Fos-GFP reporter for 413 cells. d) Fold-change images for 20 example cells at various time points relative to the start of the behavior session. e) Fold-change values and smoothed time courses for the first 12 cells in (d). f) Percentiles of the distribution of fold-change values as a function of time from the start of the behavior session. g) Median fold-change curve across all cells. n = 413 cells, 1 session, 1 mouse.
