Extended Data Fig. 6: IAA and NPA coordination of PIN1.
From: Structural insights into auxin recognition and efflux by Arabidopsis PIN1
a, Structural comparisons between the apo and IAA-bound structure of PIN1. b, Residues surrounding the IAA binding site remain almost identical in the apo and IAA-bound structures. c, Structural comparisons between the apo and NPA-bound structure of PIN1. d, Residues surrounding the NPA binding site undergo subtle rearrangements. e, Chemical structures of IAA and NPA. f, Superposition of the IAA-bound and NPA-bound structures of PIN1. g, The benzoic group of NPA binds to a pocket formed by TM5 and the crossover regions of TM4 and TM9. Surface electrostatic potential is shown for PIN1.
