Extended Data Fig. 9: Comparison of Org 274179-0 bound- and CS-17 bound TSHR EM maps.
From: Autoantibody mimicry of hormone action at the thyrotropin receptor
a) Org 274179-0 bound-TSHR EM density map (dark) fit into the CS-17-bound TSHR map (colored by TSHR-CS-17 model). b) CS-17-bound TSHR model fit into Org 274179-0 bound-TSHR map, suggesting that inactive state TSHR ECD orientations are similar between CS-17 and Org 274179-0-bound states.
