Extended Data Fig. 3: Site-selective C–H alkynylation and allylation of aza-arenes.
From: Molecular editing of aza-arene C–H bonds by distance, geometry and chirality
a, C6 (and related)-selective C–H alkynylation of aza-arenes. b, C6 (and related)-selective C–H allylation of aza-arenes. c, C7 (and related)-selective C–H alkynylation of aza-arenes. All yields are isolated yields. aUsing trans-5-decene (3 equiv). bUsing trans-4-methyl-2-pentene (3 equiv). cUsing 1-hexene (3 equiv). dUsing (S,S)-T25 (0.3 equiv), Pd(OAc)2 (20 mol%), Ac-L-Phe-OH (40 mol%), alkynylation reagent (4 equiv), 100 °C. TBAF, tetra-n-butylammonium fluoride.
