Extended Data Fig. 6: Model predicted time courses of responses to p70S6K and Trk inhibitors. | Nature

Extended Data Fig. 6: Model predicted time courses of responses to p70S6K and Trk inhibitors.

From: Control of cell state transitions

Extended Data Fig. 6

Experimental data (dots) are imposed on model predicted time course of signaling responses of TrkA and TrkB cells treated with (A) S6K inhibitor (LY2584702, 1 μM) or (B) Trk inhibitor (SP600125, 5 μM) and stimulated with 100 ng/ml NGF and BDNF, respectively. Dashed lines are the time courses in the absence of inhibitor. TrkA, blue; TrkB, red. Data are presented as mean values +/− SEM for n = 3 biologically independent experiments.

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