Extended Data Fig. 7: Comparison of the Sr35 prediction (AlphaFold2) with the Sr35 protomer from the cryo-EM structure.
From: A wheat resistosome defines common principles of immune receptor channels
a, Structural alignment of WHD and LRR domains from Sr35 AlphaFold2 prediction (cyan) and from Sr35 resistosome Cryo-EM structure (blue). b, Structural comparison of monomeric Sr35 from prediction (left) and from Cryo-EM structure (right). Substantial differences exist highlighting the structural re-organization within the NOD module (NBD-HD1 relative to WHD). Domain color code: coiled-coil (yellow), NBD (light pink), HD1 (cyan), WHD (purple), and LRR (blue).
