Extended Data Fig. 6: Per-gene dN/dS analysis of drivers (n = 1,253 CRCs).
From: Phenotypic plasticity and genetic control in colorectal cancer evolution
a, Per-gene dN/dS for the 69 IntOGen drivers in TCGA colon and rectal cohorts split into (a) missense mutations and (b) truncating mutations. Many genes have dN/dS value ≈1 indicating lack of evidence for positive selection. The points show the point estimates and the error bars the 95% CI intervals of the dN/dS
