Fig. 2: Water molecules mediate key longitudinal and lateral contacts in F-actin.
From: Bending forces and nucleotide state jointly regulate F-actin structure
a, Water molecules (violet) contained within the filament core of ADP–F-actin. Actin subunits are shown in transparent grey main-chain representation. b, Solvent-mediated contacts at lateral (top) and longitudinal (bottom) interfaces in ADP–F-actin (shades of blue) and ADP-Pi–F-actin (shades of orange). Key side chains and backbone atoms are displayed and coloured by heteroatom. Water molecules are shown in violet, and putative hydrogen bonds are indicated by dashed lines. Protomer indices are indicated.
