Extended Data Fig. 2: Resolution of cryo-EM reconstructions.

a-d, Fourier shell correlation (FSC) plots between half-maps, mask used for determination of the average resolution at FSC 0.143, orientation distribution plot, directional (3D FSC) and local resolution estimates for the consensus map (a), wing focused map (b), protomer focused map (c) and Sea2-Sea3 focused map (d).