Extended Data Fig. 10: Single cell RNAseq of tumour tissues.
From: Ferroptosis of tumour neutrophils causes immune suppression in cancer
CT26 TB mice were treated with liproxstatin-1 for 8 days. Tumours were collected and analysed by scRNAseq. a. UMAP visualization of cell populations; b. Gene set enrichment analysis of differentially expressed genes at adjusted p value < 0.01 for liproxstatin-1 treated vs DMSO treated CD4+ and CD8+ T cells. Enrichment p-values were calculated as described in fgsea R package and p-values were adjusted using Benjamini-Hochberg method.
